Key figures

1:Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction

2: Khera M, Goldstein I. Erectile dysfunction. BMJ Clin Evid. 2011 Jun 29;2011. pii: 1803.

3: Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int. 1999 Jul;84(1):50-6

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1: Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction

1: Scientific American, august 2000, 283, 2: p 70-75

2: Goldstein I. Male sexual circuitry. Working Group for the Study of Central Mechanisms in Erectile Dysfunction. Sci Am. 2000
Aug;283(2):70-5.

1: Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. 

http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html. Accessed June 2017.

2: Goldstein I. Male sexual circuitry. Working Group for the Study of Central Mechanisms in Erectile Dysfunction. Sci Am. 2000 Aug;283(2):70-5.

http://www.clinicalevidence.com.

3: Diabetic Neuropathy.

https://www.mayoclinic.org/diseasesconditions/diabetic-neuropathy/symptoms-causes/syc-20371580 Accessed 2/2/18

4: Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.

http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html. Accessed June 2017.

5: Diabetes, Sexual, & Bladder Problems. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.

https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/sexual-bladder-problems

6: Walsh TJ, Hotaling JM, Smith A, Saigal C, Wessells H. Men with diabetes may require more aggressive treatment for ED. Int J of Impotence Research 2013; 26:112-115

7: Erectile dysfunction (ED). NIH: National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/treatment

8: Malavige, S. Lasantha. Erectile dysfunction in diabetes mellitus. J Sex Med 2009; 6:1232-1247.

9:  Erectile Dysfunction and Diabetes WebMD Medical Reference

https://www.webmd.com/erectile-dysfunction/guide/ed-diabete

10: Gandaglia G, Briganti A, Jackson G et al. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014 (65):968-978.

11: What is Coronary Heart Disease? (n.d.) Retrieved from

https://www.nhlbi.nih.gov/health/health-topics/topics/cad

12: Thompson IM, Tangen CM, Goodman PJ et al. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005; 294(23):2996-3002.

13: Gandaglia G, Briganti A, Jackson G et al. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014 (65):968-978.

Messina LE, Claro JA, Nardozza A, Andrade E, Ortiz V, Srougi M.Erectile dysfunction in patients with chronic renal failure. Int Braz J Urol. 2007 Sep-Oct;33(5):673-8.Costa MR, Ponciano VC, Costa TR, Gomes CP, de Oliveira EC. Stage effect of chronic kidney disease in erectile function. Int Braz J Urol. 2018 Jan-Feb;44(1):132-140.

14: Bronner G, Aharon-Peretz J, Hassin-Baer S. Sexuality in patients with Parkinson’s disease, Alzheimer’s disease, and other dementias. Handb Clin Neurol. 2015;130:297-323.

Zeiss AM, Davies HD, Wood M, Tinklenberg JR. The incidence and correlates of erectile problems in patients with Alzheimer’s disease. Arch Sex Behav. 1990 Aug;19(4):325-31.

15: www.sexhealthmatters.org/erectile-dysfunction/penile-implants-erectile-dysfunction/P7

16: www.webmd.com/erectile-dysfunction/guide/understanding-ed-causes#1

17: www.webmd.com/erectile-dysfunction/guide/understanding-ed-causes#

20: Gandaglia G, Briganti A, Jackson G et al. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014 (65):968-978.

1: Validation of the Erection Hardness Score, Mulhall J.-P. et al., Journal of Sexual Medicine 2007″

2: Braun 2000 Braun M, Wassmer G, Klotz T, Reifenrath B, Mathers M, Engelmann U.

Epidemiology of erectile dysfunction: results of the ‘Cologne Male Survey’.

Int J Impot Res. 2000 Dec;12(6):305-11)

3: Yafi FA, Jenkins L, Albersen M, Corona G, Isidori AM, Goldfarb S, Maggi M, Nelson CJ, Parish S, Salonia A, Tan R, Mulhall JP, Hellstrom WJ. Erectile dysfunction. Nat Rev Dis Primers. 2016 Feb 4;2:16003.

http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html. Accessed June 2017.

4: Mulhall JP, Goldstein I, Bushmakin AG, Cappelleri JC, Hvidsten K. Validation of the erection hardness score. J Sex Med. 2007
Nov;4(6):1626-34.

https://www.webmd.com/erectile-dysfunction/guide/ed-diabetes

5:Sexual and Urologic Problems of Diabetes. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.

https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction

6:Walsh TJ, Hotaling JM, Smith A, Saigal C, Wessells H. Men with diabetes may require more aggressive treatment for ED. Int J of Impotence Research 2013; 26:112-115

7:Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html.

1: Malavige, S. Lasantha. Erectile dysfunction in diabetes mellitus. J Sex Med 2009; 6:1232-1247.

2:Malavige, S. Lasantha. Erectile dysfunction in diabetes mellitus. J Sex Med 2009; 6:1232-1247.

3:Erectile Dysfunction and Diabetes WebMD Medical Reference

https://www.webmd.com/erectile-dysfunction/guide/ed-diabetes

4:Diabetic Neuropathy.

https://www.mayoclinic.org/diseases-conditions/diabetic-neuropathy/symptoms-causes/syc-20371580 Accessed 2/2/18

5:Sexual and Urologic Problems of Diabetes. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction

6: Walsh TJ, Hotaling JM, Smith A, Saigal C, Wessells H. Men with diabetes may require more aggressive treatment for ED. Int J of Impotence Research 2013; 26:112-115

7: Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html.

1: Impotence. NIH: National Institutes of Health. https:consensus.nih.gov/1992/1992Impotence091html.htm.

2: Gandaglia G, Briganti A, Jackson G et al. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014 (65):968-978. 2.

3: Gandaglia G, Montorsi F, Montorsi P. Management of erectile dysfunction in patients with preexisting cardiovascular disease. G Ital Cardiol (Rome). 2016 May;17(5):356-62.

4: What is Coronary Heart Disease? (n.d.) Retrieved from https://www.nhlbi.nih.gov/health/health-topics/topics/cad

5: Thompson IM, Tangen CM, Goodman PJ et al. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005; 294(23):
2996-3002.

6: Gandaglia G, Montorsi F, Montorsi P. Management of erectile dysfunction in patients with preexisting cardiovascular disease. G Ital Cardiol (Rome). 2016 May;17(5):356-62.

7: Gandaglia G, Montorsi F, Montorsi P. Management of erectile dysfunction in patients with preexisting cardiovascular disease. GItal Cardiol (Rome). 2016 May;17(5):356-62.

10 et 20: Gandaglia G, Briganti A, Jackson G et al. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014 (65):968-978. 2.

1: 1 Krassioukov A, Elliott S.Neural Control and Physiology of Sexual Function: Effect of Spinal Cord Injury. Top Spinal Cord Inj Rehabil. 2017 Winter;23(1):1-10.

1: Hatzimouratidis K, Eardley I, Giuliano F, Hatzichristou D, Moncada I, Salonia A, Vardi Y, Wespes E; European Association of Urology. EAU guidelines on penile curvature. Eur Urol. 2012 Sep;62(3):543-52. update on Uroweb, March 2017, https://uroweb.org/guideline/ penilecurvature/?type=pocketguidelines

2: 2 Hatzimouratidis K, Eardley I, Giuliano F, Hatzichristou D, Moncada I, Salonia A, Vardi Y, Wespes E; European Association of Urology. EAU guidelines on penile curvature. Eur Urol. 2012 Sep;62(3):543-52. update on Uroweb, March 2017, https://uroweb.org/guideline/ penilecurvature/?type=pocketguidelines

1: CA: A Cancer Journal for Clinicians 2018

1: What is Coronary Heart Disease? (n.d.) Retrieved from

https://www.nhlbi.nih.gov/health/health-topics/topics/cad

2: Thompson IM, Tangen CM, Goodman PJ et al. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005; 294(23):2996-3002.

3:Gandaglia G, Montorsi F, Montorsi P. Management of erectile dysfunction in patients with preexisting cardiovascular disease. G Ital Cardiol (Rome). 2016 May;17(5):356-62.

4:Jia-Yi Dong BSc, Yong-Hong Zhang MD, PhD, Li-Qiang Qin MD.Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies. J Am Coll Cardiol. 2011 Sep 20;58(13):1378-85.

5:Imprialos KP, Stavropoulos K, Doumas M, Tziomalos K, Karagiannis A, Athyros VG. Sexual Dysfunction, Cardiovascular Risk and Effects of Pharmacotherapy. Curr Vasc Pharmacol. 2018 Jan 26;16(2):130-142. 

Sophia W. Chang, MD, MPH; Richard Fine, MD; David Siegel, MD, MPH; et al Margaret Chesney, phd; Dennis Black, PhD; Stephen B. Hulley, MD, MPH. The Impact of Diuretic Therapy on Reported Sexual Function. Arch Intern Med.  1991;151(12):2402-2408.

Margus Viigimaa, Charalambos Vlachopoulos, Antonios Lazaridis, and Michael Doumas Management of erectile dysfunction in hypertension: Tips and tricks. World J Cardiol. 2014 Sep 26; 6(9): 908–915. )

1:Khera M, Goldstein I. 2011. Erectile dysfunction. BMJ Clinical Evidence. http://www.clinicalevidence.com.

2:https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/diagnosis-treatment/drc-20355782

3:https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/diagnosis-treatment/drc-20355782

4:https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/treatment

5:https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/diagnosis-treatment/drc-20355782

6:Caverject™ Prescribing information. Pharmacia & Upjohn Company. Revised October 2016.

7:https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/diagnosis-treatment/drc-20355782

8:https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/diagnosis-treatment/drc-20355782

10:Dealing with Erectile Dysfunction. UCLA Urology. https://www.uclahealth.org/urology/mens-clinic/erectile-dysfunction Accessed September 2007.

1: Cassidy A, Franz M, Rimm EB. Dietary flavonoid intake and incidence of erectile dysfunction.Am J Clin Nutr. 2016 Feb;103(2):534-41

1: Author: Rosen RC, Psychogenic Erectile Dysfunction : Classification and Management. Urol Clin North Am. 2001 May;28(2):269-78 ).

2: Author: F.Hedon. Anxiety and erectile dysfunction: a global approach to ED enhances results and quality of life. Int J Impot Res. 2003 Apr;15 Suppl 2:S16-9.

1: Cookson MS, Nadig PW. Long-term results with vacuum constriction device.J Urol. 1993 Feb;149(2):290-4.

2: Kirby M. Best practice guidelines on the use of vacuum constriction devices for erectile dysfunction following radical prostatectomy . British Society for Sexual Medicine. January 2011. Produced and published by Owen mumford Ltd, Brook Hill, Woodstock, Oxon.

3: Lin,H;Wang,R. The science of vacuum erectile device in penile rehabilitation after radical prostatectomy. Translational andrology and urology 2013. Vol. 2 (1)P.61-66

1: Khera M, Goldstein I. Erectile dysfunction. BMJ Clin Evid. 2011 Jun 29;2011. pii: 1803.

2-3: https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/diagnosis-treatment/drc-20355782

1: Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html. Accessed June 2017.

2: https//www.sexhealthmatters.org/erectile-dysfunction/penile-implants-erectile-dysfunction/P5

3:  http://urology.ucla.edu/prostate-cancer/dealing-with-erectile-dysfunction

5:  https://www.webmd.com/erectile-dysfunction/guide/erectile-dysfunction-treatment#1

3:7. Habous M, Malleabe (Semi-Rigid) penile prosthesis. J Sex Med. 2015; 12:1984-1988.

2: Coloplast Titan®, Titan ® OTR and Titan® Touch Inflatable Penile Prosthesis Instructions for Use. Coloplast Corp. 2016.

1:Coloplast Genesis® Malleable Penile Prosthesis Instructions for Use. Coloplast Corp. 2014.

2:Habous M, Malleabe (Semi-Rigid) penile prosthesis. J Sex Med. 2015; 12:1984-1988.

1:Dealing with Erectile Dysfunction. UCLA Urology. http://urology.ucla.edu/dealing-with-erectile-dysfunction

2:Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html.

3:Savoie, Marc et al. A Prospective Study Measuring Penile Length in Men Treated with Radical Prostatectomy for Prostate Cancer. J Urol. 2003; 169:1462-1464.

4:Wilson, Steven et al. Long-Term Survival of Inflatable Penile Prostheses: Single Surgical Group Experience with 2,384 First-Time Implants Spanning Two Decades. J. Sex Med. 2007; 4:1074-1079.

5:Coloplast Titan®, Titan ® OTR and Titan® Touch Inflatable Penile Prosthesis Instructions for Use. Coloplast Corp. 2016.

6. Coloplast Genesis® Malleable Penile Prosthesis Instructions for Use. Coloplast Corp. 2014.

* Patient Educator has received compensation from Coloplast to provide their testimonial. Each person’s situation is unique
so your experience may not be the same.

1. Rajpurkar A, Dhabuwala CB. Comparison of Satisfaction Rates
and Erectile Function in Patients Treated with Sildenafil, Intracavernous Prostaglandin E1 and Penile Implant Surgery for Erectile Dysfunction in Urology Practice. J Urol. 2003; 170:159-163.
2. Khera M, Goldstein I. 2011. Erectile dysfunction. BMJ Clinical Evidence. http://www.clinicalevidence.com.

1: Erectile Dysfunction and Diabetes WebMD Medical Reference https://www.webmd.com/erectile-dysfunction/guide/ed-diabetes

2: Malavige, S. Lasantha. Erectile dysfunction in diabetes mellitus. J Sex Med 2009; 6:1232-1247.

3: Sexual and Urologic Problems of Diabetes. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction

4: Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. http://www.nlm.nih.gov/medlineplus/erectiledysfunction.html.

1. Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.

https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction

Mulhall JP, Goldstein I, Bushmakin AG, Cappelleri JC, Hvidsten K. Validation of the erection hardness score. J Sex Med. 2007 Nov;4(6):1626-34.

Goldstein I. Male sexual circuitry. Working Group for the Study of Central Mechanisms in Erectile Dysfunction. Sci Am. 2000 Aug;283(2):70-5.

Cookson MS, Nadig PW. Long-term results with vacuum constriction device. J Urol. 1993 Feb;149(2):290-4.

1:Cappelleri JC, Rosen RC. The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience. Int J Impot Res. 2005 Jul-Aug;17(4):307-19.

1: Nikhil K. Gupta, Josh Ring, Landon Trost, Steven K. Wilson, Tobias S. Köhler. The penoscrotal surgical approach for inflatable penile prosthesis placement. Transl Androl Urol 2017;6(4):628-63

2: Wang R, Howard GE, Hoang A, et al. Prospective and long-term evaluation of erect penile length obtained with inflatable penile prosthesis to that induced by intracavernosal injection. Asian J Androl 2009;11:411 5.
3: Dr Morel Journel – Coloplast interview
4: Levine LA, Becher EF, Bella AJ, Brant WO, Kohler TS, Martinez-Salamanca JI, Trost L, Morey AF.Penile Prosthesis Surgery: Current Recommendations From the International Consultation on Sexual Medicine.)(J Sex Med. 2016 Apr;13(4):489-518. doi: 10.1016/j.jsxm.2016.01.017. Epub 2016 Mar 25. Review. Erratum in: J Sex Med. 2016 Jul;13(7):1145.)

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[1] Nikhil K. Gupta, Josh Ring, Landon Trost, Steven K. Wilson, Tobias S. Köhler. The penoscrotal surgical approach for inflatable penile prosthesis placement.

Transl Androl Urol 2017;6(4):628-63

[2] Dr Morel Journel – Coloplast interview

[3] Wang R, Howard GE, Hoang A, et al. Prospective and long-term evaluation of erect penile length obtained with inflatable penile prosthesis to that induced by intracavernosal injection. Asian J Androl 2009;11:411-5.

[4] Levine LA, Becher EF, Bella AJ, Brant WO, Kohler TS, Martinez-Salamanca JI, Trost L, Morey AF.Penile Prosthesis Surgery: Current Recommendations From the International Consultation on Sexual Medicine.) (J Sex Med. 2016 Apr;13(4):489-518. doi: 10.1016/j.jsxm.2016.01.017. Epub 2016 Mar 25. Review. Erratum in: J Sex Med. 2016 Jul;13(7):1145.)

[5] Erectile dysfunction. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction